IN 1988, NITRIC OXIDE (NO ) WAS RELATED TO SOFT TISSUE RELAXATION IN THE PENIS, ALLOWING THE ORGAN TO BECOME ENGORGED. EIGHT YEARS LATER, VIAGRA CAME TO THE U.S. MARKET..
COVID HOSPITALS HAVE KILLED PATIENTS BY PUTTING PURE OXYGEN FACE MASKS AND DEPRIVING THEM OF NITROGEN.
NO CAN BE ADMINISTERED AS INHALED GAS, IN LOW CONCENTRATIONS, TO BOOST THE BLOOD-OXYGEN SATURATION LEVEL.
THE ATMOSPHERE HAS 78% NITROGEN AND 21% OXYGEN FOR A GOOD REASON.
INHALED NITRIC OXIDE ( NO) WAS FOUND TO BE EFFECTIVE AGAINST THE SARS-COV VIRUS DURING THE SARS OUTBREAK IN 2002-04.. THIS IS BEING KEPT AS A GREAT SECRET BY KOSHER COVID VACCINE MANUFACTURERS.
IN INDIA WE HINDUS WORSHIP A BLACK STINE CALLED SHIVA LINGAM ( SHIVA’S HUMAN SEEDING PENIS ) FOR A REASON.
YOGIS USED TO DO SWARA YOGA PRODUCE NTRIC OXIDE AND LIFT MASSIVE ST0NES WITH THEIR ERECT PRICKS AT FULL BLOOD ENGORGED TUMESCENCE..
FCUK YOUR WOMAN THIS WAY AND THEN ORDER HER TO MAKE “FRY EGGE” , AND WATCH THE WAY SHE RUNS LIKE USAIN BOLT TO THE KITCHEN.
A MASSIVE METEORIT STRIKE 65 MILLION YEARS AGO, REDUCED THE OXYGEN PERCENTAGE IN THE PLANET’S ATMOSPHERE AND INCREASED THE NITROGEN PERCENTAGE.
THIS KILLED OFF ALL DINOSAURS WHO NEED MORE OXYGEN TO SURVIVE AND SET THE STAGE FOR HUMANS TO BE BORN FROM DNA PROVIDED BY THE METERORITE STONES FALLING FROM SPACE.
HUMAN’S CANNOT SURVIVE WITHOUT PRODUCTION OF NITRIC OXIDE.
NO DEFICIENCY INCLUDE: INSOMNIA, HIGH BLOOD PRESSURE, ANXIETY, LOSS OF LIBIDO/AND/OR ERECTILE DYSFUNCTION, FLAGGING STAMINA, ETC.
THE HUMAN BODY NATURALLY PRODUCES NITRIC OXIDE AT ALL TIMES, AND THE MAIN SITES FOR ITS PRODUCTION IS THE INNER LINING (ENDOTHELIUM) OF OUR ARTERIES AND VEINS, ESPECIALLY IN THE LUNGS. IT IS ALSO PRODUCED IN THE CIRCULATING WBCS OF THE BODY.
THE NITRIC OXIDE PRODUCED BY THESE WBCS, COMBINED WITH OTHER MOLECULES ALSO PRODUCED BY THESE CELLS, FORM AGENTS THAT DESTROY HARMFUL BACTERIA, PARASITES AND VIRUSES.
PRANAYAMA PRODUCING NITRIC OXIDE BY MMM SOUND OF HINDU KING AMNTA OM HAS BEEN USED FOR BRONCODILATION FOR MILLINIUMS IN AYURVEDA AND YOGA..
NO LEVELS WERE SIGNIFICANTLY LOWER IN PATIENTS WITH COVID-19, WHICH WAS SUGGESTED TO BE CLOSELY RELATED TO VASCULAR DYSFUNCTION AND IMMUNE INFLAMMATION AMONG THEM..
COVID-19 VIRUS SHARES A LARGE PART OF ITS GENOME WITH THE SARS-COV VIRUS..
INFLAMMATION IN THE PATIENTS’ LUNGS DECREASES WITH NO ADMINISTRATION.. NO IS SOMETHING THE HUMAN BODY CAN PRODUCE ON ITS OWN BY PRANAYAMA..
NITRIC OXIDE IS THE ONLY SUBSTANCE SHOWN SO FAR TO HAVE A DIRECT EFFECT ON SARS-COV-2- . READ THIS LINE A ZILLION TIMES.
THE VASCULAR ENDOTHELIUM IS A MONOLAYER OF CELLS BETWEEN THE VESSEL LUMEN AND THE VASCULAR SMOOTH MUSCLE CELLS. NITRIC OXIDE (NO) IS A SOLUBLE GAS CONTINUOUSLY SYNTHESIZED FROM THE AMINO ACID L-ARGININE IN ENDOTHELIAL CELLS BY THE CONSTITUTIVE CALCIUM-CALMODULIN-DEPENDENT ENZYME NITRIC OXIDE SYNTHASE (NOS).
THIS SUBSTANCE HAS A WIDE RANGE OF BIOLOGICAL PROPERTIES THAT MAINTAIN VASCULAR HOMEOSTASIS, INCLUDING MODULATION OF VASCULAR DILATOR TONE, REGULATION OF LOCAL CELL GROWTH, AND PROTECTION OF THE VESSEL FROM INJURIOUS CONSEQUENCES OF PLATELETS AND CELLS CIRCULATING IN BLOOD, PLAYING IN THIS WAY A CRUCIAL ROLE IN THE NORMAL ENDOTHELIAL FUNCTION..
A GROWING LIST OF CONDITIONS, INCLUDING THOSE COMMONLY ASSOCIATED AS RISK FACTORS FOR ATHEROSCLEROSIS SUCH AS HYPERTENSION, HYPERCHOLESTEROLEMIA, SMOKING, DIABETES MELLITUS AND HEART FAILURE ARE ASSOCIATED WITH DIMINISHED RELEASE OF NITRIC OXIDE INTO THE ARTERIAL WALL EITHER BECAUSE OF IMPAIRED SYNTHESIS OR EXCESSIVE OXIDATIVE DEGRADATION.
THE DECREASED PRODUCTION OF NO IN THESE PATHOLOGICAL STATES CAUSES SERIOUS PROBLEMS IN ENDOTHELIAL EQUILIBRIUM AND THAT IS THE REASON WHY NUMEROUS THERAPIES HAVE BEEN INVESTIGATED TO ASSESS THE POSSIBILITY OF REVERSING ENDOTHELIAL DYSFUNCTION BY ENHANCING THE RELEASE OF NITRIC OXIDE FROM THE ENDOTHELIUM.
NITRIC OXIDE (NO) IS SYNTHESIZED IN THE VASCULAR ENDOTHELIUM FROM THE SUBSTRATE L-ARGININE IN A REACTION CATALYSED BY ENDOTHELIAL NITRIC OXIDE SYNTHASE. THIS MEDIATOR INFLUENCES THE FUNCTION OF CIRCULATING CELLS AND UNDERLYING SMOOTH MUSCLE TO CONTRIBUTE TO THE TONIC ATHEROPROTECTIVE, THROMBORESISTANT AND VASODILATOR INFLUENCE OF THE ENDOTHELIUM.
DYSFUNCTION OF THE ENDOTHELIAL NO PATHWAY CONTRIBUTES TO THE PATHOPHYSIOLOGY OF A VARIETY OF CARDIOVASCULAR DISORDERS INCLUDING ESSENTIAL HYPERTENSION, ATHEROSCLEROSIS AND PRE-ECLAMPSIA.
INHALED NO HAS BEEN USED IN CLINICAL SETTINGS FOR ITS ANTIVIRAL RESPIRATORY ACTION, AND IN THE REGULATION OF BLOOD PRESSURE TO AVOID CLOT FORMATION.
DUE TO ITS SMALL SIZE, NEUTRAL CHARGE, AND RELATIVE LIPOPHILICITY, NO DIFFUSION THROUGH CELL MEMBRANES IS FACILITATED EVEN IN THE ABSENCE OF CHANNELS OR RECEPTORS..
NO ACTION RELIES ON CERTAIN MAIN MECHANISMS, SUCH AS IMPAIRMENT OF PATHOGEN REPLICATION, INTERFERENCE IN THE ELECTRON TRANSPORT CHAIN, PROMOTION OF S-NITROSATION REACTIONS IN CYSTEINE RESIDUES OF IMPORTANT PATHOGEN ENZYMES, AND GENERATION OF OXYGEN AND NITROGEN REACTIVE SPECIES (NOX)..
NO HAS BEEN WIDELY STUDIED FOR COMBATING TUMOR CELLS, BACTERIA, FUNGI, PROTOZOA, AND VIRUSES..
SYSTEMIC ADMINISTRATION IS ALSO POSSIBLE USING NO DONORS, WHICH ARE MOLECULES ABLE TO RELEASE NO IN THE BIOLOGICAL MEDIUM, AND/OR BY ALLYING NO AND NO DONORS WITH GOLD NANOCOLLOIDS..
SYSTEMIC ADMINISTRATION IS A ROUTE OF ADMINISTRATION OF MEDICATION, NUTRITION OR OTHER SUBSTANCE INTO THE CIRCULATORY SYSTEM SO THAT THE ENTIRE BODY IS AFFECTED.
ADMINISTRATION CAN TAKE PLACE VIA ENTERAL ADMINISTRATION (ABSORPTION OF THE DRUG THROUGH THE GASTROINTESTINAL TRACT) OR PARENTERAL ADMINISTRATION (GENERALLY INJECTION, INFUSION, OR IMPLANTATION..
THE USE OF NO DONORS AND NANOMATERIALS INCREASES THE STABILITY OF NO AND ENABLES TARGETED, CONTROLLED NO RELEASE AT DESIRABLE CONCENTRATIONS, WHICH IS FUNDAMENTAL FOR NO BIOACTIVITY
NO NOT ONLY PRESENTS ANTIVIRAL ACTIVITY, BUT ALSO ACTS TO MODULATE HOST RESPONSE..
NO IS ALSO PRODUCED ENDOGENOUSLY FROM ARGININE BY HUMANS.
NO DIRECTLY SUPPRESSES THE GROWTH OF THE INFECTIOUS VIRUS IN THE LUNGS, THUS PREVENTING ITS SPREAD. IT DILATES THE AIRWAYS, WHICH HELPS DELIVER MORE OXYGEN TO THE LUNGS AND THE BLOODSTREAM. IT ENABLES THE DILATION OF THE PULMONARY ARTERIES TO ENSURE BETTER BLOOD FLOW TO THE LUNGS.
NO RELEASED FROM S-NITROSO-N-ACETYLPENICILLAMINE (SNAP) HAS A DISTINCT ANTIVIRAL EFFECT. .
S-Nitroso-N-acetylpenicillamine (SNAP) IS THE CHEMICAL COMPOUND WITH THE FORMULA ONSC(CH3)2CH(NHAc)CO2H.
JAYALALITHAA WAS PUT ON ECMO MACHINE AND SHE DIED. SHE WOULD HAVE SURVIVED IF NO-releasing delivery platforms IS PROPERLY UNDERSTOOD.
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